Antioxidants and Exercise

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Jan Karlsson
1997
US Price: $40
224 pages
9780873228961

About the Author | Table of Contents | Words of Praise

 

In this ground-breaking book Dr. Jan Karlsson presents his latest findings on nutratherapy, focusing on vitamins Q E, and F1 and how they relate to exercise, sports, and health.

 

Among the world's leading researchers on radicals and antioxidants, Karlsson explains the relationship between

• nutratherapy and preventive medicine,
• muscle metabolism and radical-antioxidant biology,
• muscle biochemistry and food choices, and
• foods, food supplements, and physical performance.

Clearly written and thoroughly illustrated, Antioxidants and Exercise contains the latest research on nutratherapy and how it can enhance performance.

About the Author

Jan Karlsson, PhD, has conducted academic research on muscle metabolism for more than 30 years and on radicals and antioxidants for more than 15 years.

Karlsson served as a visiting professor in the Institute for Biomedical Research at the University of Texas-Austin from 1981 to 1991. He was director of the Human Performance Laboratory at Karolinska Hospital in Stockholm, Sweden, from 1977 to 1982, and acting professor in sport exercise physiology at the Karolinska Institute from 1974 to 1977. Karlsson received his DrSci in 1971 and completed his post-doctoral work at Parkland Memorial Hospital in Dallas, Texas, in 1974.

Karlsson has written more than 250 articles and reviews about muscle physiology, molecular cardiology, exercise physiology, clinical cardiology, and drug testing, and he serves as a consultant to several major international pharmaceutical companies. He has received awards for his contributions in exercise medicine and drug development in Finland, the former West Germany, and Japan.

Table of Contents

• Part I: Introduction to Nutraology
  • Chapter 1. Introduction
    • History of radical and antioxidant science
    • Topics to be discussed
    • Applicability of nutratherapy to recreational exercise and elite sports
  • Chapter 2. Historical Perspective
    • Introduction of new concepts
    • Nutratherapy and health promotion
    • Vitamin terminology
    • Vitamins and enzymology
    • Earlier nutraceutical concepts
    • Nutratherapy as a potential risk factor
    • Radical trauma in people who exercise
    • Summary
• Part II: Radical Formation
  • Chapter 3. Principles of Radical Formation
    • Definition of the term radical
    • Metabolism and radical formation
    • Radical formation in the service of life
    • Radical formation and cell protection: The antioxidant strategy
    • Principles of the cascade reaction
    • Fenton reactions
    • Summary
  • Chapter 4. Principles of Radical Quenching
    • Uniqueness of phenol structures
    • Phenol species and their scavenging potentials
    • Radical scavenging
    • Water solubility and antioxidant allocation
    • Other antioxidant compounds
    • Quenching of singlet oxygen
    • Summary
  • Chapter 5. Recycling Systems or Irreversible Reactions?
    • Design of recycling systems in biology
    • Vitamin Q as a coenzyme in mitochondria
    • Antioxidants and reversible processes/reactions
    • Irreversible reactions
    • Vitamin Q, mitogenic ligands, and training
    • Cycling antioxidants and antioxidant enzymes
    • Summary
  • Chapter 6. Radical Formation in Different Cells and Tissues
    • Muscle activity and mitochondrial metabolism
    • Muscle exercise, purine metabolism, and radicals
    • Endothelial tissue
    • White blood cells and radical formation
    • Mixed items
    • Concept of overuse injury
    • Summary
  • Chapter 7. Exercising Muscle and Radical Formation
    • Biological evidence of free radicals
    • Summary
  • Chapter 8. Nutrients as Antioxidants and Their Food Sources
    • Food sources for antioxidant nutrients
    • Antioxidant-related nutrients
    • Summary
  • Chapter 9. Exercise, Mixed Diets, and Nutratherapy
    • Muscle exercise and its limitation
    • Muscle activity and energy intake
    • Energy intake and "natural nutrients"
    • Elite sport activity and antioxidant nutratherapy
    • Inflammatory processes and nutratherapy
    • Diet antioxidants or nutratherapy
    • Antioxidant and omega-3 fatty acid nutratherapy
    • Antioxidants and other nutrients
    • Summary
  • Chapter 10. Lipoidic Structures, Lipophilic Antioxidants, and Clinical Interpretations
    • Antioxidant allocation and its significance
    • Antioxidants in different organs and tissues
    • Plasma lipophilic antioxidants and their "normalization"
    • Vitamins Q and E in plasma HDL and LDL particles
    • Vitamins Q and E and their transport vehicle- LDL
    • Vitamins Q and E and their turnover: A role for HDL?
    • Endowment and/or training adaptation and antioxidants
    • Summary
• Part III: Nutratherapy and Sports Medicine
  • Chapter 11. Relevant Studies
    • Antioxidant vitamins and placebo-controlled studies
    • Antioxidant supplements and open studies
    • Good clinical trial practice studies
    • Nutraceutical preparation of the 1994 Swedish World Cup soccer team
    • Cross-country skiing, plasma antioxidants, and food supplements
    • Summary
  • Chapter 12. Nutratherapy, Dose Response, and Side Effects
    • Nutratherapies and their pharmacokinetics
    • Antioxidant supplemenets and tissue changes
    • Dose-response curves for antioxidants
    • Standardized or individualized nutratherapy?
    • Side effects of Vitamins Q, E, and F1
    • Summary
  • Chapter 13. Nutrients, Pharmaceutical Grade, and The Doping Issue
    • Supplement products and good manufacturing practice (GMP)
    • Nutraceutical therapy, ergogenic aids, and sport ethics
    • Elite sports, "drugs," and the doping rules
• Part IV
• Conclusions

Words of Praise

"Readers of this book will be enlightened about the effects of certain antioxidants. The book is an excellent source for researchers in the field of exercise and sports science, graduate students, coaches, sport participants, and individuals who want to learn about how supplementation or diet with vitamin E and vitamin Q may be important for better health."

Dr. Alan Goldfarb
Associate Professor
Department of Exercise and Sports Science
University of North Carolina-Greensboro

Audiences

A reference for exercise physiologists, sport nutritionists, sports medicine professionals, and muscle physiologists.